Brain Cancer PCR Array Primer Libraries

Brain cancer represents a group of benign and malignant neoplasms arising from neural tissue. The most common types are glioblastoma, astrocytoma and meningiomas. Medulloblastomas occur in children. Overall 5-year survival rate for this class of disease in 33%. The molecular basis for brain cancers is largely unknown and may involve dysregulated RTK signaling pathways and mutations occurring in key oncogenes. A number of biomarkers have been identified, but there overall usefulness in diagnosis and prognosis remains an active area of investigation. The Human Brain Cancer PCR Primer Library contains primer sets designed to amplify the components of key signaling pathways and biomarkers associated with brain cancers.