T-Cell Development/Differentiation

T cells undergo thymic development and differentiate into distinct subsets defined by cytokine production and effector functions. This development depends upon Notch and Wnt signaling pathways and transcription factors. T cells develop from pluripotent precursors that migrate to the thymus where they proliferate, develop and differentiate. The T-Cell Development/Differentiation Primer Library contains primer sets to measure gene expression associated with these processes.