Human Statin Signaling Library

Contains 88 primer sets directed against statin signaling genes and 8 housekeeping gene primer sets.

Provided in a 96-well microplate (20 ul - 10 uM)

Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction)

Just add cDNA template and SYBR green master mix



GENE LIST:

ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1

ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5

ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8

ACAT2 Acetyl-CoA acetyltransferase 2

AKT1 V-akt murine thymoma viral oncogene homolog 1

APOA1 Apolipoprotein A-I

APOA2 Apolipoprotein A-II

APOA4 Apolipoprotein A-IV

APOA5 Apolipoprotein A-V

APOB Apolipoprotein B (including Ag(x) antigen)

APOC1 Apolipoprotein C-I

APOC2 Apolipoprotein C-II

APOC3 Apolipoprotein C-III

APOE Apolipoprotein E

BAX BCL2-associated X protein

BCL2 B-cell CLL/lymphoma 2

BCL2L1 BCL2-like 1

BDNF Brain-derived neurotrophic factor

CASP3 Caspase 3, apoptosis-related cysteine peptidase

CASP7 Caspase 7, apoptosis-related cysteine peptidase

CASP9 Caspase 9, apoptosis-related cysteine peptidase

CAV1 Caveolin 1, caveolae protein, 22kDa

CD40 CD40 molecule, TNF receptor superfamily member 5

CDC42 Cell division cycle 42 (GTP binding protein, 25kDa)

CETP Cholesteryl ester transfer protein, plasma

CYP3A4 Cytochrome P450, family 3, subfamily A, polypeptide 4

CYP3A5 Cytochrome P450, family 3, subfamily A, polypeptide 5

CYP7A1 Cytochrome P450, family 7, subfamily A, polypeptide 1

DGAT1 Diacylglycerol O-acyltransferase 1

ELK1 ELK1, member of ETS oncogene family

FASN Fatty acid synthase

FDFT1 Farnesyl-diphosphate farnesyltransferase 1

GSK3B Glycogen synthase kinase 3 beta

HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase

HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

IFNG Interferon, gamma

IKBKB Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

IKBKE Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

IKBKG Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

IL1B Interleukin 1, beta

IL2 Interleukin 2

IL5 Interleukin 5 (colony-stimulating factor, eosinophil)

IL6 Interleukin 6 (interferon, beta 2)

JUN Jun proto-oncogene

KLF2 Kruppel-like factor 2 (lung)

LCAT Lecithin-cholesterol acyltransferase

LDLR Low density lipoprotein receptor

LIPC Lipase, hepatic

LPL Lipoprotein lipase

LRP1 Low density lipoprotein receptor-related protein 1

LSS Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)

MAPK1 Mitogen-activated protein kinase 1

MAPK10 Mitogen-activated protein kinase 10

MAPK14 Mitogen-activated protein kinase 14

MAPK3 Mitogen-activated protein kinase 3

MDM2 Mdm2 p53 binding protein homolog (mouse)

MTOR Mechanistic target of rapamycin (serine/threonine kinase)

MTTP Microsomal triglyceride transfer protein

NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

NGF Nerve growth factor (beta polypeptide)

NOS3 Nitric oxide synthase 3 (endothelial cell)

PDIA2 Protein disulfide isomerase family A, member 2

PDK1 Pyruvate dehydrogenase kinase, isozyme 1

PLTP Phospholipid transfer protein

PPARA Peroxisome proliferator activated receptor alpha

PPARD Peroxisome proliferator-activated receptor delta

PPARG Peroxisome proliferator-activated receptor gamma

PPARGC1A Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

PPARGC1B Peroxisome proliferator-activated receptor gamma, coactivator 1 beta

PTEN Phosphatase and tensin homolog

PTGS2 Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

RAC1 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

REL V-rel reticuloendotheliosis viral oncogene homolog (avian)

RELA V-rel reticuloendotheliosis viral oncogene homolog A (avian)

ROCK1 Rho-associated, coiled-coil containing protein kinase 1

SCARB1 Scavenger receptor class B, member 1

SCD Stearoyl-CoA desaturase (delta-9-desaturase)

SIRT1 Sirtuin 1

SMAD3 SMAD family member 3

SMAD4 SMAD family member 4

SOAT1 Sterol O-acyltransferase 1

SQLE Squalene epoxidase

SREBf1 Sterol regulatory element binding transcription factor 1

SREBf2 Sterol regulatory element binding transcription factor 2

TGFB1 Transforming growth factor, beta 1

TLR4 Toll-like receptor 4

TNF Tumor necrosis factor

VEGFA Vascular endothelial growth factor A

ACTB Actin, beta

B2M Beta-2-microglobulin

GAPD Glyceraldehyde-3-phosphate dehydrogenase

GUSB Glucuronidase, beta

HPRT1 Hypoxanthine phosphoribosyltransferase 1

PGK Phosphoglycerate kinase 1

PPIA Peptidylprolyl isomerase A

RPL13A Ribosomal protein L13a