Human p53 Signaling Primer Library

Contains 88 primer sets directed against TP53 signaling genes and 8 housekeeping gene primer sets.

Provided in a 96-well microplate (20 ul - 10 uM)

Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction)

Just add cDNA template and SYBR green master mix



GENE LIST:

ACTA2 actin, alpha 2, smooth muscle, aorta

APAF1 apoptotic peptidase activating factor 1

ATF3 activating transcription factor 3

ATM ataxia telangiectasia mutated

ATR ataxia telangiectasia and Rad3 related

BAI1 brain-specific angiogenesis inhibitor 1

BAX BCL2-associated X protein

BBC3 BCL2 binding component 3

BCL2 B-cell CLL/lymphoma 2

BCL2A1 BCL2-related protein A1

BID BH3 interacting domain death agonist

BIRC5 baculoviral IAP repeat containing 5

BRCA1 breast cancer 1, early onset

BRCA2 breast cancer 2, early onset

BTG2 BTG family, member 2

CASP2 caspase 2, apoptosis-related cysteine peptidase

CASP9 caspase 9, apoptosis-related cysteine peptidase

CCNB2 cyclin B2

CCNE2 cyclin E2

CCNG2 cyclin G2

CCNH cyclin H

CDC2 cyclin-dependent kinase 2

CDC25A cell division cycle 25 homolog A (S. pombe)

CDK4 cyclin-dependent kinase 4

CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)

CDKN2A cyclin-dependent kinase inhibitor 2A

CHEK1 checkpoint kinase 1

CHEK2 checkpoint kinase 2

CRADD CASP2 and RIPK1 domain containing adaptor with death domain

DNMT1 DNA (cytosine-5-)-methyltransferase 1

E2F1 E2F transcription factor 1

EGR1 early growth response 1

EGR1 early growth response 1

ESR1 estrogen receptor 1

ESR2 estrogen receptor 2 (ER beta)

FADD Fas (TNFRSF6)-associated via death domain

FAS Fas (TNF receptor superfamily, member 6)

FASLG Fas ligand (TNF superfamily, member 6)

FOXP3 forkhead box P3

GADD45A growth arrest and DNA-damage-inducible, alpha

GADD45G growth arrest and DNA-damage-inducible, gamma

HDAC1 histone deacetylase 1

HIF1A hypoxia inducible factor 1, alpha subunit

HK2 hexokinase 2

IFNB1 interferon, beta 1, fibroblast

IGF1R insulin-like growth factor 1 receptor

IL6 interleukin 6 (interferon, beta 2)

JUN jun proto-oncogene

KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

MCL1 myeloid cell leukemia sequence 1 (BCL2-related)

MDM2 Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)

MDM4 Mdm4 p53 binding protein homolog (mouse)

MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)

MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)

MYC V-myc myelocytomatosis viral oncogene homolog

MYOD1 myogenic differentiation 1

NF1 neurofibromin 1

NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

P53AIP1 tumor protein p53 regulated apoptosis inducing protein 1

PCAF P300/CBP-associated factor

PCBP4 poly(rC) binding protein 4

PCNA proliferating cell nuclear antigen

PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D

PRC1 protein regulator of cytokinesis 1

PRKCA protein kinase C, alpha

PTEN phosphatase and tensin homolog

PTTG1 pituitary tumor-transforming 1

RB1 retinoblastoma 1

RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian)

RPRM reprimo, TP53 dependent G2 arrest mediator candidate

SESN1 sestrin 1

SESN2 sestrin 2

SIAH1 siah E3 ubiquitin protein ligase 1

SIRT1 sirtuin 1

STAT1 signal transducer and activator of transcription 1, 91kDa

TADA3L transcriptional adaptor 3 (NGG1 homolog, yeast)- like

TNF tumor necrosis factor

TNFRSF10B tumor necrosis factor receptor superfamily, member 10b

TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

TP53 tumor protein p53

TP53BP2 tumor protein p53 binding protein, 2

TP53I3 tumor protein p53 inducible protein 3

TP53INP1 tumor protein p53 inducible nuclear protein 1

TP73 tumor protein p73

TP63 tumor protein p63

TRAF2 TNF receptor-associated factor 2

TSC1 tuberous sclerosis 1

WT1 Wilms tumor 1

ACTB Actin, beta

B2M Beta-2-microglobulin

GAPD Glyceraldehyde-3-phosphate dehydrogenase

GUSB Glucuronidase, beta

HPRT1 Hypoxanthine phosphoribosyltransferase 1

PGK Phosphoglycerate kinase 1

PPIA Peptidylprolyl isomerase A

RPL13A Ribosomal protein L13a