Human Cancer Driver Gene I Primer Library

Contains 88 primer sets directed against putative cancer driver genes and 8 housekeeping gene primer sets.

Provided in a 96-well microplate (20 ul - 10 uM)

Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction)

Just add cDNA template and SYBR green master mix



GENE LIST:

ACVR1B activin A receptor, type IB

ACVR2A activin A receptor, type IIA

AKT1 v-akt murine thymoma viral oncogene homolog 1

ALB albumin

ALK anaplastic lymphoma receptor tyrosine kinase

AMOT angiomotin

APC adenomatous polyposis coli

ARHGAP35 Rho GTPase activating protein 35

ARID1A AT rich interactive domain 1A (SWI-like)

ARID1B AT rich interactive domain 1B (SWI1-like)

ARID2 AT rich interactive domain 2 (ARID, RFX-like)

ARID4B AT rich interactive domain 4B (RBP1-like)

ASXL1 additional sex combs like transcriptional regulator 1

ATG5 autophagy related 5

ATM ATM serine/threonine kinase

ATRX alpha thalassemia/mental retardation syndrome X- linked

AXIN1 axin 1

B2M beta-2-microglobulin

BAP1 BRCA1 associated protein-1 (ubiquitin carboxy- terminal hydrolase)

BCLAF1 BCL2-associated transcription factor 1

BCOR BCL6 corepressor

BRAF B-Raf proto-oncogene, serine/threonine kinase

BRCA1 breast cancer 1, early onset

BRCA2 breast cancer 2, early onset

BRE brain and reproductive organ-expressed (TNFRSF1A modulator)

CASP8 caspase 8, apoptosis-related cysteine peptidase

CBFB core-binding factor, beta subunit

CCAR1 cell division cycle and apoptosis regulator 1

CCND1 cyclin D1

CDC73 cell division cycle 73

CDH1 cadherin 1, type 1, E-cadherin (epithelial)

CDK12 cyclin-dependent kinase 12

CDK4 cyclin-dependent kinase 4

CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)

CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)

CDKN2A cyclin-dependent kinase inhibitor 2A

CEBPA CCAAT/enhancer binding protein (C/EBP), alpha

CHD4 chromodomain helicase DNA binding protein 4

CHD8 chromodomain helicase DNA binding protein 8

CHEK2 checkpoint kinase 2

CIC Capicua transcriptional repressor

CNOT1 CCR4-NOT transcription complex, subunit 1

CNOT4 CCR4-NOT transcription complex, subunit 4

CREBBP CREB binding protein

CSDE1 cold shock domain containing E1, RNA-binding

CTCF CCCTC-binding factor (zinc finger protein)

CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa

CUL1 cullin 1

CUL2 cullin 2

DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked

DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5

DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15

DICER1 dicer 1, ribonuclease type III

DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease

DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha

EGFR epidermal growth factor receptor

EIF1AX eukaryotic translation initiation factor 1A, X- linked

EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3

EIF4A2 eukaryotic translation initiation factor 4A2

ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )

EP300 E1A binding protein p300

EPHA2 EPH receptor A2

ERBB2 erb-b2 receptor tyrosine kinase 2

ERBB3 erb-b2 receptor tyrosine kinase 3

EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit

FAT1 FAT atypical cadherin 1

FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase

FGFR1 fibroblast growth factor receptor 1

FGFR2 fibroblast growth factor receptor 2

FGFR3 fibroblast growth factor receptor 3

FLT3 fms-related tyrosine kinase 3

FN1 fibronectin 1

FOXA1 forkhead box A1

FUBP1 far upstream element (FUSE) binding protein 1

FUS FUS RNA binding protein

GATA3 GATA binding protein 3

GPS2 G protein pathway suppressor 2

HGF hepatocyte growth factor (hepapoietin A; scatter factor)

HLA-A major histocompatibility complex, class I, A

HLA-B major histocompatibility complex, class I, B

HRAS Harvey rat sarcoma viral oncogene homolog

HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1

IDH1 isocitrate dehydrogenase 1 (NADP+), soluble

IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial

KDM5C lysine (K)-specific demethylase 5C

KDM6A lysine (K)-specific demethylase 6A

KEAP1 kelch-like ECH-associated protein 1

KLF4 Kruppel-like factor 4 (gut)

ACTB Actin, beta

B2M Beta-2-microglobulin

GAPDH Glyceraldehyde-3-phosphate dehydrogenase

GUSB Glucuronidase, beta

HPRT1 Hypoxanthine phosphoribosyltransferase 1

PGK1 Phosphoglycerate kinase 1

PPIA Peptidylprolyl isomerase A

RPL13A Ribosomal protein L13a