Human Cancer Driver Gene II Primer Library

Contains 88 primer sets directed against putative cancer driver genes and 8 housekeeping gene primer sets.

Provided in a 96-well microplate (20 ul - 10 uM)

Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction)

Just add cDNA template and SYBR green master mix



GENE LIST:

KRAS Kirsten rat sarcoma viral oncogene homolog

KRT15 keratin 15, type I

MAP2K1 mitogen-activated protein kinase kinase 1

MAP2K4 mitogen-activated protein kinase kinase 4

MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3

MAPK1 mitogen-activated protein kinase 1

MAX MYC associated factor X

MED12 mediator complex subunit 12

MED23 mediator complex subunit 23

MEN1 multiple endocrine neoplasia I

MGA MGA, MAX dimerization protein

MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

MTOR mechanistic target of rapamycin (serine/threonine kinase)

MYC v-myc myelocytomatosis viral oncogene homolog (avian)

MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog

MYD88 myeloid differentiation primary response 88

NCOA2 nuclear receptor coactivator 2

NCOR1 nuclear receptor corepressor 1

NF1 neurofibromin 1

NF2 neurofibromin 2 (merlin)

NFE2L2 nuclear factor, erythroid 2-like 2

NKX3-1 NK3 homeobox 1

NOTCH1 notch 1

NOTCH2 notch 2

NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)

NRAS neuroblastoma RAS viral (v-ras) oncogene homolog

NSD1 nuclear receptor binding SET domain protein 1

PBRM1 polybromo 1

PCBP1 poly(rC) binding protein 1

PHF6 PHD finger protein 6

PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D

PPP2R1A protein phosphatase 2, regulatory subunit A, alpha

PPP6C protein phosphatase 6, catalytic subunit

PSIP1 PC4 and SFRS1 interacting protein 1

PTEN phosphatase and tensin homolog

PTPN11 protein tyrosine phosphatase, non-receptor type 11

RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

RAF1 Raf-1 proto-oncogene, serine/threonine kinase

RASA1 RAS p21 protein activator (GTPase activating protein) 1

RB1 retinoblastoma 1

RBM10 RNA binding motif protein 10

RFC4 replication factor C (activator 1) 4, 37kDa

RHEB Ras homolog enriched in brain

RHOA ras homolog family member A

RIT1 Ras-like without CAAX 1

RPL5 ribosomal protein L5

RUNX1 runt-related transcription factor 1

SETD1B SET domain containing 1B

SETD2 SET domain containing 2

SF3A3 splicing factor 3a, subunit 3, 60kDa

SF3B1 splicing factor 3b, subunit 1, 155kDa

SFPQ splicing factor proline/glutamine-rich

SIN3A SIN3 transcription regulator family member A

SMAD2 SMAD family member 2

SMAD4 SMAD family member 4

SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

SOS1 son of sevenless homolog 1 (Drosophila)

SOX9 SRY (sex determining region Y)-box 9

SPOP speckle-type POZ protein

STAG2 stromal antigen 2

STK11 serine/threonine kinase 11

TBL1XR1 transducin (beta)-like 1 X-linked receptor 1

TBX3 T-box 3

TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG- box)

TET2 tet methylcytosine dioxygenase 2

TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)

TGFBR2 transforming growth factor, beta receptor II (70/80kDa)

THRAP3 thyroid hormone receptor associated protein 3

TP53 tumor protein p53

TP53BP1 tumor protein p53 binding protein 1

TRAF3 TNF receptor-associated factor 3

TSC1 tuberous sclerosis 1

TTR transthyretin

U2AF1 U2 small nuclear RNA auxiliary factor 1

USP28 ubiquitin specific peptidase 28

VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase

WT1 Wilms tumor 1

XPO1 exportin 1

ZFHX3 zinc finger homeobox 3

ZFP36L1 ZFP36 ring finger protein-like 1

ZFP36L2 ZFP36 ring finger protein-like 2

ZNF292 zinc finger protein 292

ZNF750 zinc finger protein 750

ACTB Actin, beta

B2M Beta-2-microglobulin

GAPDH Glyceraldehyde-3-phosphate dehydrogenase

GUSB Glucuronidase, beta

HPRT1 Hypoxanthine phosphoribosyltransferase 1

PGK1 Phosphoglycerate kinase 1

PPIA Peptidylprolyl isomerase A

RPL13A Ribosomal protein L13a