SYBR Green qPCR primers for detecting human CHRNA4 (cholinergic receptor nicotinic alpha 4 subunit) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human CHRNA4 qPCR Primer Set – cholinergic receptor nicotinic alpha 4 subunit
Also known as: BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4
About this gene: CHRNA4 encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. The CHRNA4 protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor.
Gene details: NCBI Gene ID: 1137; HGNC ID: HGNC:1958; UniProt: P43681; RefSeq (MANE Select): NM_000744.7; Chromosome location: 20q13.33
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.