SYBR Green qPCR primers for detecting human CHEK2 (checkpoint kinase 2, also called hCds1) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human CHEK2 qPCR Primer Set – checkpoint kinase 2
Also known as: CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, TPDS4, hCds1
About this gene: In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The CHEK2 protein is a cell cycle checkpoint regulator and putative tumor suppressor. The CHEK2 gene product contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage.
Gene details: NCBI Gene ID: 11200; HGNC ID: HGNC:16627; UniProt: O96017; RefSeq (MANE Select): NM_007194.4; Chromosome location: 22q12.1
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.