Neurotransmitters carry signals between neurons and from neurons to muscles and glands. Major neurotransmitters include glutamate, GABA, glycine, acetylcholine, dopamine, serotonin, norepinephrine and neuropeptides. They are synthesized by specific enzymes, packaged into synaptic vesicles, released by calcium triggered exocytosis, and act on ionotropic (ligand gated ion channel) and metabotropic (G protein coupled) receptors. Signaling is ended by reuptake transporters and degrading enzymes such as MAOA and COMT. Changes in neurotransmitter signaling underlie many neurological and psychiatric disorders.
A ready-to-use Human Neurotransmitter Signaling PCR primer library that may be used to set up to 100 PCR arrays. Contains 88 primer sets directed against neurotransmitter signaling genes and 8 housekeeping gene primer sets. Provided in a 96-well microplate (20 ul - 10 uM) Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction) Just add cDNA template and SYBR green master mix GENE LIST: ABAT 4-aminobutyrate aminotransferase ACHE acetylcholinesterase (Yt blood group) BSN bassoon presynaptic cytomatrix protein CCKAR cholecystokinin A receptor CCKBR cholecystokinin B receptor CHAT choline O-acetyltransferase CHRM1 cholinergic receptor, muscarinic 1 CHRM2 cholinergic receptor, muscarinic 2 CHRM3 cholinergic receptor, muscarinic 3 CHRM4 cholinergic receptor, muscarinic 4 CHRM5 cholinergic receptor, muscarinic 5 CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) CHRND cholinergic receptor, nicotinic, delta (muscle) CHRNE cholinergic receptor, nicotinic, epsilon (muscle) CHRNG cholinergic receptor, nicotinic, gamma (muscle) COMT catechol-O-methyltransferase DRD1 dopamine receptor D1 DRD2 dopamine receptor D2 DRD3 dopamine receptor D3 GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 GABRD gamma-aminobutyric acid (GABA) A receptor, delta GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 GABRP gamma-aminobutyric acid (GABA) A receptor, pi GABRQ gamma-aminobutyric acid (GABA) A receptor, theta GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 GAD1 glutamate decarboxylase 1 (brain, 67kDa) GALR1 galanin receptor 1 GALR2 galanin receptor 2 GALR3 galanin receptor 3 GCH1 GTP cyclohydrolase 1 GLRA1 glycine receptor, alpha 1 GLRA2 glycine receptor, alpha 2 GLRA3 glycine receptor, alpha 3 GLRB glycine receptor, beta GPR83 G protein-coupled receptor 83 GRIA1 glutamate receptor, ionotropic, AMPA 1 GRIK4 glutamate receptor, ionotropic, kainate 4 GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 GRPR gastrin-releasing peptide receptor Htr1A 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic MAOA monoamine oxidase A NMUR1 neuromedin U receptor 1 NMUR2 neuromedin U receptor 2 PHOX2A paired-like homeobox 2a PPYR1 Pancreatic polypeptide receptor 1 RIMS1 regulating synaptic membrane exocytosis 1 RIMS3 regulating synaptic membrane exocytosis 3 RIMS4 regulating synaptic membrane exocytosis 4 SNPH syntaphilin SORCS1 sortilin-related VPS10 domain containing receptor 1 SORCS2 sortilin-related VPS10 domain containing receptor 2 SSTR1 somatostatin receptor 1 SSTR2 somatostatin receptor 2 STX1A syntaxin 1A (brain) STX1B syntaxin 1B SYP synaptophysin SYT1 synaptotagmin I TACR1 tachykinin receptor 1 TACR2 tachykinin receptor 2 TPH1 tryptophan hydroxylase 1 TSPO translocator protein (18kDa) ACTB Actin, beta B2M Beta-2-microglobulin GAPDH Glyceraldehyde-3-phosphate dehydrogenase GUSB Glucuronidase, beta HPRT1 Hypoxanthine phosphoribosyltransferase 1 PGK1 Phosphoglycerate kinase 1 PPIA Peptidylprolyl isomerase A RPL13A Ribosomal protein L13a $495.00 |
A ready-to-use Mouse Neurotransmitter Signaling PCR primer library that may be used to set up to 100 PCR arrays. Contains 88 primer sets directed against neurotransmitter signaling genes and 8 housekeeping gene primer sets. Provided in a 96-well microplate (20 ul - 10 uM) Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction) Just add cDNA template and SYBR green master mix GENE LIST: Abat 4-aminobutyrate aminotransferase Ache acetylcholinesterase (Yt blood group) Bsn bassoon presynaptic cytomatrix protein Cckar cholecystokinin A receptor Cckbr cholecystokinin B receptor Chat choline O-acetyltransferase Chrm1 cholinergic receptor, muscarinic 1 Chrm2 cholinergic receptor, muscarinic 2 Chrm3 cholinergic receptor, muscarinic 3 Chrm4 cholinergic receptor, muscarinic 4 Chrm5 cholinergic receptor, muscarinic 5 Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) Chrna3 cholinergic receptor, nicotinic, alpha 3 (neuronal) Chrna4 cholinergic receptor, nicotinic, alpha 4 (neuronal) Chrna5 cholinergic receptor, nicotinic, alpha 5 (neuronal) Chrna6 cholinergic receptor, nicotinic, alpha 6 (neuronal) Chrna7 cholinergic receptor, nicotinic, alpha 7 (neuronal) Chrnb1 cholinergic receptor, nicotinic, beta 1 (muscle) Chrnb2 cholinergic receptor, nicotinic, beta 2 (neuronal) Chrnb3 cholinergic receptor, nicotinic, beta 3 (neuronal) Chrnb4 cholinergic receptor, nicotinic, beta 4 (neuronal) Chrnd cholinergic receptor, nicotinic, delta (muscle) Chrne cholinergic receptor, nicotinic, epsilon (muscle) Chrng cholinergic receptor, nicotinic, gamma (muscle) Comt catechol-O-methyltransferase Drd1 dopamine receptor D1 Drd2 dopamine receptor D2 Drd3 dopamine receptor D3 Gabbr1 gamma-aminobutyric acid (GABA) B receptor, 1 Gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 Gabra2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 Gabra3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Gabra6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 Gabrb1 gamma-aminobutyric acid (GABA) A receptor, beta 1 Gabrb2 gamma-aminobutyric acid (GABA) A receptor, beta 2 Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 Gabrd gamma-aminobutyric acid (GABA) A receptor, delta Gabre gamma-aminobutyric acid (GABA) A receptor, epsilon Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 Gabrg2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 Gabrp gamma-aminobutyric acid (GABA) A receptor, pi Gabrq gamma-aminobutyric acid (GABA) A receptor, theta Gabrr1 gamma-aminobutyric acid (GABA) A receptor, rho 1 Gabrr2 gamma-aminobutyric acid (GABA) A receptor, rho 2 Gad1 glutamate decarboxylase 1 (brain, 67kDa) Galr1 galanin receptor 1 Galr2 galanin receptor 2 Galr3 galanin receptor 3 Gch1 GTP cyclohydrolase 1 Glra1 glycine receptor, alpha 1 Glra2 glycine receptor, alpha 2 Glra3 glycine receptor, alpha 3 Glrb glycine receptor, beta Gpr83 G protein-coupled receptor 83 Gria1 glutamate receptor, ionotropic, AMPA 1 Grik4 glutamate receptor, ionotropic, kainate 4 Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 Grpr gastrin-releasing peptide receptor Htr1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Htr1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled Htr2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Htr2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Htr3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic Maoa monoamine oxidase A Nmur1 neuromedin U receptor 1 Nmur2 neuromedin U receptor 2 Phox2A paired-like homeobox 2a Ppyr1 Pancreatic polypeptide receptor 1 Rims1 regulating synaptic membrane exocytosis 1 Rims3 regulating synaptic membrane exocytosis 3 Rims4 regulating synaptic membrane exocytosis 4 Snph syntaphilin Sorcs1 sortilin-related VPS10 domain containing receptor 1 Sorcs2 sortilin-related VPS10 domain containing receptor 2 Sstr1 somatostatin receptor 1 Sstr2 somatostatin receptor 2 Stx1A syntaxin 1A (brain) Stx1B syntaxin 1B Syp synaptophysin Syt1 synaptotagmin I Tacr1 tachykinin receptor 1 Tacr2 tachykinin receptor 2 Tph1 tryptophan hydroxylase 1 Tspo translocator protein (18kDa) Actb Actin, beta B2M Beta-2-microglobulin Gapdh Glyceraldehyde-3-phosphate dehydrogenase Gusb Glucuronidase, beta Hprt1 Hypoxanthine phosphoribosyltransferase 1 Pgk1 Phosphoglycerate kinase 1 Ppia Peptidylprolyl isomerase A Rpl13A Ribosomal protein L13a $495.00 |
A ready-to-use Rat Neurotransmitter Signaling PCR primer library that may be used to set up to 100 PCR arrays. Contains 88 primer sets directed against neurotransmitter signaling genes and 8 housekeeping gene primer sets. Provided in a 96-well microplate (20 ul - 10 uM) Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction) Just add cDNA template and SYBR green master mix GENE LIST: Abat 4-aminobutyrate aminotransferase Ache acetylcholinesterase (Yt blood group) Bsn bassoon presynaptic cytomatrix protein Cckar cholecystokinin A receptor Cckbr cholecystokinin B receptor Chat choline O-acetyltransferase Chrm1 cholinergic receptor, muscarinic 1 Chrm2 cholinergic receptor, muscarinic 2 Chrm3 cholinergic receptor, muscarinic 3 Chrm4 cholinergic receptor, muscarinic 4 Chrm5 cholinergic receptor, muscarinic 5 Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) Chrna3 cholinergic receptor, nicotinic, alpha 3 (neuronal) Chrna4 cholinergic receptor, nicotinic, alpha 4 (neuronal) Chrna5 cholinergic receptor, nicotinic, alpha 5 (neuronal) Chrna6 cholinergic receptor, nicotinic, alpha 6 (neuronal) Chrna7 cholinergic receptor, nicotinic, alpha 7 (neuronal) Chrnb1 cholinergic receptor, nicotinic, beta 1 (muscle) Chrnb2 cholinergic receptor, nicotinic, beta 2 (neuronal) Chrnb3 cholinergic receptor, nicotinic, beta 3 (neuronal) Chrnb4 cholinergic receptor, nicotinic, beta 4 (neuronal) Chrnd cholinergic receptor, nicotinic, delta (muscle) Chrne cholinergic receptor, nicotinic, epsilon (muscle) Chrng cholinergic receptor, nicotinic, gamma (muscle) Comt catechol-O-methyltransferase Drd1 dopamine receptor D1 Drd2 dopamine receptor D2 Drd3 dopamine receptor D3 Gabbr1 gamma-aminobutyric acid (GABA) B receptor, 1 Gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 Gabra2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 Gabra3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Gabra6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 Gabrb1 gamma-aminobutyric acid (GABA) A receptor, beta 1 Gabrb2 gamma-aminobutyric acid (GABA) A receptor, beta 2 Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 Gabrd gamma-aminobutyric acid (GABA) A receptor, delta Gabre gamma-aminobutyric acid (GABA) A receptor, epsilon Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 Gabrg2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 Gabrp gamma-aminobutyric acid (GABA) A receptor, pi Gabrq gamma-aminobutyric acid (GABA) A receptor, theta Gabrr1 gamma-aminobutyric acid (GABA) A receptor, rho 1 Gabrr2 gamma-aminobutyric acid (GABA) A receptor, rho 2 Gad1 glutamate decarboxylase 1 (brain, 67kDa) Galr1 galanin receptor 1 Galr2 galanin receptor 2 Galr3 galanin receptor 3 Gch1 GTP cyclohydrolase 1 Glra1 glycine receptor, alpha 1 Glra2 glycine receptor, alpha 2 Glra3 glycine receptor, alpha 3 Glrb glycine receptor, beta Gpr83 G protein-coupled receptor 83 Gria1 glutamate receptor, ionotropic, AMPA 1 Grik4 glutamate receptor, ionotropic, kainate 4 Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 Grpr gastrin-releasing peptide receptor Htr1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Htr1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled Htr2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Htr2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Htr3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic Maoa monoamine oxidase A Nmur1 neuromedin U receptor 1 Nmur2 neuromedin U receptor 2 Phox2A paired-like homeobox 2a Ppyr1 Pancreatic polypeptide receptor 1 Rims1 regulating synaptic membrane exocytosis 1 Rims3 regulating synaptic membrane exocytosis 3 Rims4 regulating synaptic membrane exocytosis 4 Snph syntaphilin Sorcs1 sortilin-related VPS10 domain containing receptor 1 Sorcs2 sortilin-related VPS10 domain containing receptor 2 Sstr1 somatostatin receptor 1 Sstr2 somatostatin receptor 2 Stx1A syntaxin 1A (brain) Stx1B syntaxin 1B Syp synaptophysin Syt1 synaptotagmin I Tacr1 tachykinin receptor 1 Tacr2 tachykinin receptor 2 Tph1 tryptophan hydroxylase 1 Tspo translocator protein (18kDa) Actb Actin, beta B2M Beta-2-microglobulin Gapdh Glyceraldehyde-3-phosphate dehydrogenase Gusb Glucuronidase, beta Hprt1 Hypoxanthine phosphoribosyltransferase 1 Pgk1 Phosphoglycerate kinase 1 Ppia Peptidylprolyl isomerase A Rpl13A Ribosomal protein L13a $595.00 |