Mouse Tumor Invasion/Metastasis Primer Library

Contains 88 primer sets directed against tumor invasion/metastasis genes and 8 housekeeping gene primer sets.

Provided in a 96-well microplate (20 ul - 10 uM)

Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction)

Just add cDNA template and SYBR green master mix



GENE LIST:

Adamts1 ADAM metallopeptidase

Aldh3a1 Aldehyde dehydrogenase 3 family, memberA1

Angpt1 Angiopoietin 1

Angptl4 Angiopoietin-like 4

Casp8 Caspase 8, apoptosis-related cysteine peptidase

Ccne2 Cyclin E2

Ccr7 Chemokine (C-C motif) receptor 7

Cd44 CD44 molecule (Indian blood group)

Cd82 CD82 antigen

Cdh1 Cadherin 1, type 1, E-cadherin (epithelial)

Cdh11 Cadherin 11, type 2, OB-cadherin (osteoblast)

Cdh2 Cadherin 2, type 1, N-cadherin

Cdh6 Cadherin 6

Cldn7 Claudin 7

Col1a1 Collagen, type I, alpha 1

Col4a2 Collagen, type IV, alpha 2

Col6a1 Collagen, type VI, alpha 1

Csf1 Colony stimulating factor 1 (macrophage)

Csf3 Colony stimulating factor 3 (granulocyte)

Cst7 Cystatin F (leukocystatin)

Ctgf Connective tissue growth factor

Ctsb Cathepsin B

Ctsd Cathepsin D

Ctsk Cathepsin K

Ctsl1 Cathepsin L-like 3

Cxcl1 Chemokine (C-X-C motif) ligand 1

Cxcl12 Chemokine (C-X-C motif) ligand 12

Cxcr4 Chemokine (C-X-C motif) receptor 4

Cxcr6 Chemokine (C-X-C motif) receptor 6

Drg1 Developmentally regulated GTP binding protein 1

Ereg Epiregulin

Fgf8 Fibroblast growth factor 8 (androgen-induced)

Flt1 Fms-related tyrosine kinase

Flt4 Fms-related tyrosine kinase 4

Gpi Glucose phosphate isomerase

Gsn Gelsolin (amyloidosis, Finnish type)

Hgf Hepatocyte growth factor (hepapoietin A; scatter factor)

Hif1a Hypoxia inducible factor 1, alpha subunit

Hmgb1 High-mobility group box 1

Id1 Inhibitor of DNA binding 1

Igfbp7 Insulin-like growth factor binding protein 7

Il13ra2 Interleukin 13 receptor, alpha 2

Isg20 Interferon stimulated exonuclease gene 20kDa

Jag1 Jagged 1 (Alagille syndrome)

Kiss1 KiSS-1 metastasis-suppressor

Klrc2 Killer cell lectin-like receptor subfamily C, member 2

Kynu Kynureninase (L-kynurenine hydrolase)

Ltbp1 Latent transforming growth factor beta binding protein 1

Map2k4 Mitogen-activated protein kinase kinase 4

Map2k5 Mitogen-activated protein kinase kinase 5

Map2k7 Mitogen-activated protein kinase kinase 7

Mcam Melanoma cell adhesion molecule

Met Met proto-oncogene (hepatocyte growth factor receptor)

Metap2 Methionyl aminopeptidase 2

Mmp1 Matrix metallopeptidase 1 (interstitial collagenase)

Mmp10 Matrix metallopeptidase 10 (stromelysin 2)

Mmp11 Matrix metallopeptidase 11 (stromelysin 3)

Mmp13 Matrix metallopeptidase 13 (collagenase 3)

Mmp14 Matrix metallopeptidase 14 (membrane-inserted)

Mmp2 Matrix metallopeptidase 2

Mmp7 Matrix metallopeptidase 7 (matrilysin, uterine)

Myc V-myc myelocytomatosis viral oncogene homolog

Nedd9 Neural precursor cell expressed, dev. down- regulated 9

Nf2 Neurofibromin 2 (merlin)

Nme1 Non-metastatic cells 1, protein (NM23A)

Nme2 Non-metastatic cells 2, protein

Nme4 Non-metastatic cells 4, protein

Pax5 Paired box 5

Pdgfa Platelet-derived growth factor alpha polypeptide

Plaur Plasminogen activator, urokinase receptor

Ptgs2 Prostaglandin-endoperoxide synthase 2

Runx1 Runt-related transcription factor 1

Serpine1 Serpin peptidase inhibitor, clade E

Serpinb5 Serpin peptidase inhibitor, clade B5

Sox4 SRY (sex determining region Y)-box 4

Sparc Secreted protein, acidic, cysteine-rich (osteonectin)

Spp1 Secreted phosphoprotein 1

Src V-src sarcoma viral oncogene homolog (avian)

Syk Spleen tyrosine kinase

Tff1 Trefoil factor 1

Tgfb1 Transforming growth factor, beta 1

Timp1 TIMP metallopeptidase inhibitor 1

Timp2 TIMP metallopeptidase inhibitor 2

Timp3 TIMP metallopeptidase inhibitor 3

Timp4 TIMP metallopeptidase inhibitor 4

Tnc Tenascin C (hexabrachion)

Tp53 Tumor protein p53

Vegfa Vascular endothelial growth factor A

Actb Actin, beta

B2m Beta-2-microglobulin

Gapd Glyceraldehyde-3-phosphate dehydrogenase

Gusb Glucuronidase, beta

Hprt1 Hypoxanthine phosphoribosyltransferase 1

Pgk Phosphoglycerate kinase 1

Ppia Peptidylprolyl isomerase A

Rpl13a Ribosomal protein L13a