Human MEGoptosis Primer Library

Contains 374 primer sets directed against apoptosis genes and 10 housekeeping gene primer sets.

Provided in a 384-well microplate (10 ul - 10 uM)

Perform up to 100 PCR arrays (based on 10 ul assay volume per reaction)

Just add cDNA template and SYBR green master mix



GENE LIST:

ACSF2 acyl-CoA synthetase family member 2

ACSL1 acyl-CoA synthetase long-chain family member 1

ACSL3 acyl-CoA synthetase long-chain family member 3

ACSL4 acyl-CoA synthetase long-chain family member 4

ACSL5 acyl-CoA synthetase long-chain family member 5

ACSL6 acyl-CoA synthetase long-chain family member 6

AIF allograft inflammatory factor 1

AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1

AIM2 absent in melanoma 2

AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)

AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)

AKR1C1 aldo-keto reductase family 1, member C1

AKT1S1 AKT1 substrate 1 (proline-rich)

ALDH1A1 aldehyde dehydrogenase 1 family, member A1

ALOX15 arachidonate 15-lipoxygenase

AMBRA1 Autophagy/beclin-1 regulator 1

APOL1 Apolipoprotein L, 1

ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1

ATF4 Activating transcription factor 4

ATG10 ATG10 autophagy related 10 homolog (S. cerevisiae)

ATG12 ATG12 autophagy related 12 homolog (S. cerevisiae)

ATG14 autophagy related 14

ATG16L1 ATG16 autophagy related 16-like 1 (S. cerevisiae)

ATG16L2 ATG16 autophagy related 16-like 2 (S. cerevisiae)

ATG2A ATG2 autophagy related 2 homolog A (S. cerevisiae)

ATG2B ATG2 autophagy related 2 homolog B (S. cerevisiae)

ATG3 ATG3 autophagy related 3 homolog (S. cerevisiae)

ATG4A ATG4 autophagy related 4 homolog A (S. cerevisiae)

ATG4B ATG4 autophagy related 4 homolog B (S. cerevisiae)

ATG4C ATG4 autophagy related 4 homolog C (S. cerevisiae)

ATG4D ATG4 autophagy related 4 homolog D (S. cerevisiae)

ATG5 autophagy related 5

ATG7 autophagy related 7

ATG9A ATG9 autophagy related 9 homolog A (S. cerevisiae)

ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)

AZU1 azurocidin 1

BAD BCL2-associated agonist of cell death

BAK1 BCL2-antagonist/killer 1

BARKOR BARKOR (KIAA0831)

BAX BCL2-associated X protein

BBC3 BCL2 binding component 3

BCL2 B-cell CLL/lymphoma 2

BCL2L1 BCL2-like 1

BCL2L11 BCL2-like 11

BECLIN1 Beclin1

BECN1 beclin 1, autophagy related

BECN1L1 Becn1L1

BID BH3 interacting domain death agonist

BIK BCL2-interacting killer (apoptosis-inducing)

BIRC2 baculoviral IAP repeat containing 2

BIRC3 baculoviral IAP repeat containing 3

BIRC4 baculoviral IAP repeat containing 4

BIRC5 Effector cell peptidase receptor 1

BIRC7 baculoviral IAP repeat containing 7

BMF Bcl2 modifying factor

BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3

BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like

BOK BCL2-related ovarian killer

BRAF B-Raf proto-oncogene, serine/threonine kinase

BRCA2 breast cancer 2, early onset

CAPN1 calpain 1, (mu/I) large subunit

CAPN2 calpain 2, (m/II) large subunit

CARDH Data not found

CARS1 cysteinyl-TRNA Synthetase 1 

CASP1 caspase 1, apoptosis-related cysteine peptidase

CASP10 caspase 10, apoptosis-related cysteine peptidase

CASP12 caspase 12, apoptosis-related cysteine peptidase

CASP14 caspase 14, apoptosis-related cysteine peptidase

CASP16 caspase 16, apoptosis-related cysteine peptidase (putative)

CASP2 caspase 2, apoptosis-related cysteine peptidase

CASP3 caspase 3, apoptosis-related cysteine peptidase

CASP4 caspase 4, apoptosis-related cysteine peptidase

CASP5 caspase 5, apoptosis-related cysteine peptidase

CASP6 caspase 6, apoptosis-related cysteine peptidase

CASP7 caspase 7, apoptosis-related cysteine peptidase

CASP8 caspase 8, apoptosis-related cysteine peptidase

CASP9 caspase 9, apoptosis-related cysteine peptidase

CAT catalase

CD14 CD14 molecule

CD24 CD24 molecule

CD27 CD27 molecule

CD28 CD28 molecule

CD40 CD40 molecule, TNF receptor superfamily member 5

CD70 CD70 molecule

CDH1 cadherin 1, type 1, E-cadherin (epithelial)

CDH3 cadherin 3, type 1, P-cadherin (placental)

CFLAR CASP8 and FADD-like apoptosis regulator

CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1

CISD1 CDGSH iron sulfur domain 1

CLEC9A C-type lectin domain family 9, member A

CP ceruloplasmin (ferroxidase)

CS citrate synthase

CTSG cathepsin G

CYBA cytochrome b-245, alpha polypeptide

CYBB cytochrome b-245, beta polypeptide

CYCS cytochrome c, somatic

CYLD cylindromatosis (turban tumor syndrome)

DDIT3 DNA-damage-inducible transcript 3

DIABLO diablo, IAP-binding mitochondrial protein

DMT1 dementia, familial nonspecific

DRAM Damage-regulated autophagy modulator

DUOX1 dual oxidase 1

DUOX2 dual oxidase 2

EIF4EBP1 Eukaryotic translation initiation factor 4E binding protein 1

EIF4EBP2 Eukaryotic translation initiation factor 4E binding protein 2

EIF4G1 Eukaryotic translation initiation factor 4 gamma, 1

ELANE elastase, neutrophil expressed

EMC2 ER membrane protein complex subunit 2

ENDOG endonuclease G

EPRS glutamyl-prolyl-tRNA synthetase

EPS15L1 Epidermal growth factor receptor pathway substrate 15-like 1

FADD Fas (TNFRSF6)-associated via death domain

FADD Fas (TNFRSF6)-associated via death domain

FANCD2 Fanconi anemia, complementation group D2

FAS Fas cell surface death receptor

FASLG Fas ligand (TNF superfamily, member 6)

FKBP15 FK506 binding protein 15, 133kDa

FMN1 formin 1

FRAP1 FK506 binding protein 12-rapamycin associated protein 1

FRS2 Fibroblast growth factor receptor substrate 2

FRS3 Fibroblast growth factor receptor substrate 3

FTH1 ferritin, heavy polypeptide 1

FTL ferritin, light polypeptide

FTMT ferritin mitochondrial

G6PD glucose-6-phosphate dehydrogenase

GABARAP GABA(A) receptor-associated protein

GABARAPL1 GABA(A) receptor-associated protein like 1

GABARAPL2 GABA(A) receptor-associated protein-like 2

GBL G protein beta subunit-like

GCLC glutamate-cysteine ligase, catalytic subunit

GCLM glutamate-cysteine ligase, modifier subunit

GFI1B Growth factor independent 1B transcription repressor

GLS2 glutaminase 2 (liver, mitochondrial)

GLS2 glutaminase 2 (liver, mitochondrial)

GLUD1 glutamate dehydrogenase 1

GLUL glutamate-ammonia ligase

GNAI3 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

GOT1 glutamic-oxaloacetic transaminase 1, soluble

GOT1 glutamic-oxaloacetic transaminase 1, soluble

GPSM1 G-protein signaling modulator 1 (AGS3-like, C. elegans)

GPSM2 G-protein signaling modulator 2 (AGS3-like, C. elegans)

GPSM3 G-protein signaling modulator 3 (AGS3-like, C. elegans)

GPX1 glutathione peroxidase 1

GPX2 glutathione peroxidase 2

GPX3 glutathione peroxidase 3

GPX4 glutathione peroxidase 4

GPX5 glutathione peroxidase 5

GPX6 glutathione peroxidase 6

GSDMC gasdermin C

GSDMD gasdermin D

GSDME gasdermin E

GSS glutathione synthetase

GSTA1 glutathione S-transferase alpha 1

GSTP1 glutathione S-transferase pi 1

HAMP hepcidin antimicrobial peptide

HARS histidyl-tRNA synthetase

HEPH hephaestin

HFE homeostatic Iron Regulator

HIF1A Hypoxia inducible factor 1, alpha

HMGB1 high mobility group box 1

HMGN1 high mobility group nucleosome binding domain 1

HMOX1 heme oxygenase 1

HMOX2 heme oxygenase 2

HRAS Harvey rat sarcoma viral oncogene homolog

HRK harakiri, BCL2 interacting protein

HSF1 heat shock transcription factor 1

HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1

HSP90B1 heat shock protein 90kDa beta (Grp94), member 1

HSPA1A heat shock 70kDa protein 1A

HSPA1B heat shock 70kDa protein 1B

HSPA4 heat shock 70kDa protein 4

HSPA5 Heat shock 70kDa protein 5

HSPB1 heat shock 27kDa protein 1

HTRA2 HtrA serine peptidase 2

IFI16 interferon, gamma-inducible protein 16

IKBKG inhibitor of kappa light polypeptide gene enhancer in B- cells, kinase gamma

IL18 interleukin 18

IL1A interleukin 1, alpha

IL1B interleukin 1, beta

IL1R1 interleukin 1 receptor, type I

IL1RAP interleukin 1 receptor accessory protein

IL33 interleukin 33

IREB2 iron-responsive element binding protein 2

IRF1 interferon regulatory factor 1

KAT5 K(lysine) acetyltransferase 5

KEAP1 kelch-like ECH-associated protein 1

KRAS Kirsten rat sarcoma viral oncogene homolog

LAMP1 lysosomal-associated membrane protein 1

LAMP2 Lysosomal-associated membrane protein 2

LAMP3 Lysosomal-associated membrane protein 3

LETM1 Leucine zipper-EF-hand containing transmembrane protein 1

LETM2 Leucine zipper-EF-hand containing transmembrane protein 2

LOX lysyl oxidase

LPCAT3 lysophosphatidylcholine acyltransferase 3

LRP1 low density lipoprotein receptor-related protein 1

MAP1LC3A microtubule Associated Protein 1 Light Chain 3 Alpha

MAP1LC3B Microtubule-associated protein 1 light chain 3 beta

MAP1LC3B2 Microtubule-associated protein 1 light chain 3 beta 2

MAP1LC3C Microtubule-associated protein 1 light chain 3 gamma

MAP3K7 mitogen-activated protein kinase kinase kinase 7

MAPK1 mitogen-activated protein kinase 1

MAPK3 mitogen-activated protein kinase 3

MAPK8 mitogen-activated protein kinase 8

MCL1 Myeloid cell leukemia sequence 1 (BCL2-related)

METTL3 methyltransferase like 3

MFN1 mitofusin 1

MFN2 mitofusin 2

MIF macrophage Migration Inhibitory Factor

MLKL mixed lineage kinase domain-like

MPO myeloperoxidase

NAIP NLR family, apoptosis inhibitory protein

NCOA4 nuclear receptor coactivator 4

NFE2L2 nuclear factor, erythroid 2-like 2

NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

NKX2-5 NK2 Homeobox 5

NLRC4 NLR family, CARD domain containing 4

NLRP1 NLR family, pyrin domain containing 1

NLRP3 NLR family, pyrin domain containing 3

NLRP6 NLR family, pyrin domain containing 6

NOX1 NADPH oxidase 1

NOX1 NADPH oxidase 1

NOX2 Data not found

NOX3 NADPH Oxidase 3

NOX4 NADPH Oxidase 4

NOX5 NADPH oxidase, EF-hand calcium binding domain 5

NQO1 NAD(P)H dehydrogenase, quinone 1

NRAS neuroblastoma RAS viral (v-ras) oncogene homolog

P2RX1 purinergic receptor P2X, ligand gated ion channel, 1

P2RX2 purinergic receptor P2X, ligand gated ion channel, 2

P2RX3 purinergic receptor P2X, ligand gated ion channel, 3

P2RX4 purinergic receptor P2X, ligand gated ion channel, 4

P2RX5 purinergic receptor P2X, ligand gated ion channel, 5

P2RX6 purinergic receptor P2X, ligand gated ion channel, 6

P2RX7 purinergic receptor P2X, ligand gated ion channel, 7

PADI4 peptidyl Arginine Deiminase 4

PANX1 pannexin 1

PANX2 pannexin 2

PAR PAR protein

PARG poly (ADP-ribose) glycohydrolase

PARP1 poly (ADP-ribose) polymerase 1

PARP2 poly (ADP-ribose) polymerase 2

PCBP1 poly(rC) binding protein 1

PCBP2 poly(rC) binding protein 2

PIK3C3 Phosphoinositide-3-kinase, class 3

PIK3R4 Phosphoinositide-3-kinase, regulatory subunit 4

PPARG peroxisome proliferator-activated receptor gamma

PPID peptidylprolyl isomerase D

PPIF peptidylprolyl isomerase F

PPM1K Protein phosphatase 1K (PP2C domain containing)

PRDX6 peroxiredoxin 6

PRNP prion protein

PSEN1 presenilin 1

PSMG2 Proteasome (prosome, macropain) assembly chaperone 2

PTGES2 prostaglandin E synthase 2

PYGL phosphorylase, glycogen, liver

RAB5A RAB5A, Member RAS Oncogene Family

RAB7A RAB7A, Member RAS Oncogene Family

RAPTOR Raptor

RASD1 RAS, dexamethasone-induced 1

RB1CC1 RB1-inducible coiled-coil 1

REL v-rel avian reticuloendotheliosis viral oncogene homolog

RELA v-rel avian reticuloendotheliosis viral oncogene homolog A

RELT RELT tumor necrosis factor receptor

RFK riboflavin kinase

RGS19 Regulator of G-protein signaling 19

RHOA ras homolog family member A

RICTOR Rapamycin-insensitive companion of mTOR

RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1

RIPK2 receptor-interacting serine-threonine kinase 2

RIPK3 receptor-interacting serine-threonine kinase 3

RIPK4 receptor-interacting serine-threonine kinase 4

RPL8 ribosomal protein L8

S100B S100 calcium binding protein B

SAT1 spermidine/spermine N1-acetyltransferase 1

SAT2 spermidine/spermine N1-acetyltransferase family member 2

SEC16A SEC16 homolog A (S. cerevisiae)

SEC16B SEC16 homolog B (S. cerevisiae)

SEC23A Sec23 homolog A (S. cerevisiae)

SEC23B Sec23 homolog B (S. cerevisiae)

SEC24A SEC24 related gene family, member A (S. cerevisiae)

SEC24B SEC24 related gene family, member B (S. cerevisiae)

SEC24C SEC24 related gene family, member C (S. cerevisiae)

SEC24D SEC24 related gene family, member D (S. cerevisiae)

SH3GLB1 SH3-domain GRB2-like endophilin B1

SH3GLB2 SH3-domain GRB2-like endophilin B2

SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2

SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5

SLC39A14 solute carrier family 39 (zinc transporter), member 14

SLC39A8 solute carrier family 39 (zinc transporter), member 8

SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2

SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1

SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal

SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

SNX30 Sorting nexin family member 30

SOD1 superoxide dismutase 1, soluble

SOD2 superoxide dismutase 2, mitochondrial

SOD3 superoxide dismutase 3, extracellular

SQSTM1 Sequestosome 1

STEAP3 STEAP family member 3, metalloreductase

STIM1 stromal interaction molecule 1

TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1

TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2

TF transferrin

TFEB transcription factor EB

TFR2 Transferrin Receptor 2

TFRC transferrin receptor

TLR2 toll-like receptor 2

TLR3 toll-like receptor 3

TLR3 toll-like receptor 3

TLR4 toll-like receptor 4

TMEM173 transmembrane protein 173

TNF tumor necrosis factor

TNFAIP3 tumor necrosis factor, alpha-induced protein 3

TNFAIP3 Tumor necrosis factor, alpha-induced protein 3

TNFRSF10A tumor necrosis factor receptor superfamily, member 10a

TNFRSF10B Tumor necrosis factor receptor superfamily, member 10b

TNFRSF10C Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

TNFRSF10D Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

TNFRSF11A Tumor necrosis factor receptor superfamily, member 11a, NFKB activator

TNFRSF11B Tumor necrosis factor receptor superfamily, member 11b

TNFRSF12A Tumor necrosis factor receptor superfamily, member 12A

TNFRSF13B Tumor necrosis factor receptor superfamily, member 13B

TNFRSF13C Tumor necrosis factor receptor superfamily, member 13C

TNFRSF14 Tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

TNFRSF17 Tumor necrosis factor receptor superfamily, member 17

TNFRSF18 Tumor necrosis factor receptor superfamily, member 18

TNFRSF19 Tumor necrosis factor receptor superfamily, member 19

TNFRSF1A tumor necrosis factor receptor superfamily, member 1A

TNFRSF1B tumor necrosis factor receptor superfamily, member 1B

TNFRSF21 Tumor necrosis factor receptor superfamily, member 21

TNFRSF25 tumor necrosis factor receptor superfamily, member 25

TNFRSF25 Tumor necrosis factor receptor superfamily, member 25

TNFRSF4 Tumor necrosis factor receptor superfamily, member 4

TNFRSF6B Tumor necrosis factor receptor superfamily, member 6b, decoy

TNFRSF8 Tumor necrosis factor receptor superfamily, member 8

TNFRSF9 Tumor necrosis factor receptor superfamily, member 9

TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

TNFSF11 Tumor necrosis factor (ligand) superfamily, member 11

TNFSF12 tumor necrosis factor (ligand) superfamily, member 12

TNFSF13 Tumor necrosis factor (ligand) superfamily, member 13

TNFSF13B Tumor necrosis factor (ligand) superfamily, member 13b

TNFSF14 Tumor necrosis factor (ligand) superfamily, member 14

TNFSF15 Tumor necrosis factor (ligand) superfamily, member 15

TNFSF18 Tumor necrosis factor (ligand) superfamily, member 18

TNFSF4 Tumor necrosis factor (ligand) superfamily, member 4

TNFSF8 Tumor necrosis factor (ligand) superfamily, member 8

TNFSF9 Tumor necrosis factor (ligand) superfamily, member 9

TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)

TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)

TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)

TP53 tumor protein p53

TP73 Tumor protein p73

TPR Translocated promoter region (to activated MET oncogene)

TRADD TNFRSF1A-associated via death domain

TRAF1 TNF receptor-associated factor 1

TRAF2 TNF receptor-associated factor 2

TRAF3 TNF receptor-associated factor 3

TRAF5 TNF receptor-associated factor 5

TRIM69 tripartite motif containing 69

TXN thioredoxin

TXN2 thioredoxin 2

TXNRD1 thioredoxin reductase 1

ULK1 Unc-51-like kinase 1 (C. elegans)

ULK2 Unc-51-like kinase 2 (C. elegans)

ULK3 Unc-51-like kinase 3 (C. elegans)

ULK4 Unc-51-like kinase 4 (C. elegans)

USP21 ubiquitin specific peptidase 21

UVRAG UV radiation resistance associated gene

VDAC2 voltage-dependent anion channel 2

VDAC3 voltage-dependent anion channel 3

WDR45L WDR45-like

WIPI1 WD repeat domain, phosphoinositide interacting 1

WIPI2 WD repeat domain, phosphoinositide interacting 2

ACTB Actin, beta

B2M Beta-2-microglobulin

GAPD Glyceraldehyde-3-phosphate dehydrogenase

GUSB Glucuronidase, beta

HPRT1 Hypoxanthine phosphoribosyltransferase 1

PGK Phosphoglycerate kinase 1

PPIA Peptidylprolyl isomerase A

RPL13A Ribosomal protein L13a

TBP TATA-Box Binding Protein

TFRC Transferrin Receptor